PGS - Preimplantation Genetic Screening

PGS preimplantation genetic screening

In Vitro Fertilization (IVF) has made revolutionary changes within the last 10 years. The most recent focus is on being able to make sure each pregnancy we achieve is a normal pregnancy and will lead to a normal baby.  Current technology allows for testing of the embryos through a precise biopsy of the embryo that will undergo a preimplantation screening.  A preimplantation screening of the embryos will test for abnormalities such as Down syndrome and other chromosomal abnormalities. This technology allows for the transfer of only normal embryos which therefore increases the likelihood of a successful embryo transfer and successful pregnancy.

​Here at Generation Next Fertility, we are proud to offer to our patients preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD).

Questions & Answers:

There are a number of chromosomal abnormalities that can be identified during the PGS process. These include alterations in the number of chromosomes, leading to conditions such as Down syndrome, Turner’s syndrome, and unbalanced chromosome complements that result from structural chromosome rearrangements in the parents’ genes that can cause birth defects, mental retardation and/or miscarriage. PGS provides our patients with the ability to transfer normal embryos, while also making them aware of any abnormal embryos they may have. Preimplantation genetics not only provides you with the chromosomal analysis of the embryos, but will also allow for gender selection.

PGD is performed when looking for a specific genetic disorder and its related mutations. For example, if you and your partner are found to be a carrier of a specific genetic disorder such as Cystic Fibrosis, a probe can be created to look for the specific mutations associated with that disorder in order to determine which embryos do not carry the disorder. You would then only transfer the embryos free of the specific disorder.

Following egg retrieval and fertilization, the embryos are grown to the blastocyst stage (DAY 5 – DAY 6 after retrieval). At this point, the embryos have hundreds of cells. The embryologist uses a laser to carefully dissect a few of the outer cells of the embryo, and these cells are then sent to the laboratory to determine whether the embryo has a specific genetic disorder and/or whether the embryo is chromosomally normal. These embryos are generally frozen until the genetic test results are available, and then the healthiest embryo can be thawed and transferred the following month.

​The use of this technology is one of the many ways Generation Next Fertility is always looking out for each patient’s best interest and family goals.


We are available 24 hours a day at: 212- 641-0906


Monday-Friday: 7:30am – 5:00pm
Saturday: 8:30am – 3:00pm


Monday-Friday: 7:30am – 9:30am
Saturday: 8:30am – 10:30am


By appointment only

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